BIOSIGNAL Study
| Title: | Lipoprotein(a) is associated with large artery atherosclerosis stroke aetiology and stroke recurrence among patients below the age of 60 years: results from the BIOSIGNAL study |
| Short summary: | The three-year cumulative risk of a recurrent stroke, dependent on aetiology, is up to 25 per cent. At present, preventing recurrence relies on a broad approach to reduce risk factors associated with atherosclerosis, heart disease and metabolic disorders. However, more specific interventions, such as anticoagulation and surgery or stenting, need aetiologic information. BIOSIGNAL aims to determine where the most promising candidate biomarkers can help identify stroke aetiology and also predict overall MACE, including specifically recurrent stroke. In addition, the insights gained into the processes underlying different stroke subtypes may lead to more targeted diagnostic tools.h large artery atherosclerosis (LAA) stroke and risk of recurrent cerebrovascular events in AIS patients. |
| Study design: | Prospective, observational, multicenter cohort study |
| Status: | closed |
| PI or Local PI: | Prof. Mira Katan |
| Link: | https://pubmed.ncbi.nlm.nih.gov/33709115/ |